ANTICANCER STUDY ON ALCOHOLIC EXTRACT OF CAESALPINIA CRISTA ROOT BARK EXTRACT

Authors

  • Bodakhe S. H, Agrawal Anchal1, Agrawal Ashish, Shinde Nishant, Namdeo K. P,

Abstract

Caesalpinia crista is traditionally used in the treatment of various disorders including cancer. The present study was aimed to investigate the possible anticancer activity of root bark of Caesalpinia crista. The anticancer activity of root bark of Caesalpinia crista was evaluated against the Ehrlich Ascites Carcinoma (EAC) Tumor model. The activity was assessed by using tumor volume, packed cell volume, mean survival time, increase in life span and hematological studies. Oral administration of alcoholic extract of root bark of Caesalpinia crista increased survival time and the life span. Hematological parameters which were altered by tumor inoculation were restored. Solid tumor mass was also significantly reduced. Present study establishes anticancer activity of root bark of Caesalpinia crista.

References

Downloads

Published

2014-02-23

Issue

Vol. 1 No. 4 (2011): JOURNAL OF PHARMACEUTICAL RESEARCH AND OPINION

Section

Articles

License

“I ……………………………………….certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”
How to Cite