ANTI-ARTHRITIC AND ANTI-INFLAMMATORY EFFECT OF CETYLMYRISTEOLATE AGAINST CARRAGEENAN INDUCED ACUTE ARTHRITIS

Authors

  • Kayalvizhi M.K*, Vanitha Samuel, P. Nirmala, K. Balamurugan

Abstract

To evaluate the effect of Cetylmyristeolate (CMO) in carrageenan induced
acute arthritis in rats. The experimental study was evaluated on 18
(male/female) Wister rats weighing (150 – 200gms). 0.1ml of 1%
carrageenan was injected to induce arthritis, CMO showed marked
reduction of arthritic and inflammatory effect. CMO is an effective antiarthritic
agent at 500 mg/day/p.o. From the results of this study, it was
concluded that CMO, an acetylated fatty acid ester produced a
statistically significant effect in reducing carrageenan induced arthritis in
rats.

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Published

2014-02-23

Issue

Vol. 2 No. 1 (2012): JOURNAL OF PHARMACEUTICAL RESEARCH AND OPINION

Section

Articles

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