INVESTIGATION OF ANTHELMINTIC ACTIVITY OF PODS OF CAESALPINIA PULCHERRIMA

Authors

  • Manoj Kumbhare

Abstract

The World Health Organization estimates that a staggering two billion people harbor parasitic worm infections. Helminth infections are the most common health problems in India and in developing countries. Present study evaluates the anthelmintic activity of various extracts of pods of Caesalpinia pulcherrima using Indian earthworms i.e. Pheritima posthuma (5-7cm size). Three different extracts (Petroleum ether, Chloroform and Methanolic) of pods of Caesalpinia pulcherrima at the concentration of 10, 20 and 50 mg/ml were tested. The results obtained indicate that C. pulcherrima has anthelmintic activity that supports the folk medicinal use of the plant. The effects of standard Drugs as Pipperazine citrate and albendazole (10 mg/ml) also evaluated. The results of present study indicate that the petroleum ether and chloroform extract significantly demonstrated paralysis and also caused death of worms in dose dependent manner.

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Published

2014-02-23

Issue

Vol. 2 No. 7 (2012): JOURNAL OF PHARMACEUTICAL RESEARCH AND OPINION

Section

Articles

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“I ……………………………………….certify that I have participated sufficiently in the conception and design of this work and the analysis of the data (wherever applicable), as well as the writing of the manuscript, to take public responsibility for it. I believe the manuscript represents valid work. I have reviewed the final version of the manuscript and approve it for publication. Neither has the manuscript nor one with substantially similar content under my authorship been published nor is being considered for publication elsewhere, except as described in an attachment. Furthermore I attest that I shall produce the data upon which the manuscript is based for examination by the editors or their assignees, if requested.”
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